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Ghsrtm1.1Lex
Targeted Allele Detail
Summary
Symbol: Ghsrtm1.1Lex
Name: growth hormone secretagogue receptor; targeted mutation 1.1, Lexicon Genetics
MGI ID: MGI:3821589
Synonyms: GHS-R-
Gene: Ghsr  Location: Chr3:27425500-27432159 bp, + strand  Genetic Position: Chr3, 10.86 cM
Alliance: Ghsrtm1.1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141985
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exons 1 and 2. The absence of transcript expression in the brain and pituitary was confirmed by real-time PCR. (J:141985)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ghsr Mutation:  27 strains or lines available
References
Original:  J:141985 Verhulst PJ, et al., Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice. Gastroenterology. 2008 Oct;135(4):1267-76
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory