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Plin2tm1Itl
Targeted Allele Detail
Nomenclature
Symbol: Plin2tm1Itl
Name: perilipin 2; targeted mutation 1, inGenious Targeting Laboratory
MGI ID: MGI:3820655
Synonyms: Adfpdelta2-3, Plin2tm1Igl
Gene: Plin2  Location: Chr4:86648386-86670060 bp, - strand  Genetic Position: Chr4, 40.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:142021
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neo cassette. The absence of full-length protein expression was confirmed by western blot analysis on mammary gland extracts and by immunohistochemistry on mouse retina. (J:142021)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plin2 Mutation:  8 strains or lines available
References
Original:  J:142021 Imanishi Y, et al., Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina. J Biol Chem. 2008 Sep 5;283(36):25091-102
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory