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Stk4Gt(AJ0315)Wtsi
Gene trapped Allele Detail
Nomenclature
Symbol: Stk4Gt(AJ0315)Wtsi
Name: serine/threonine kinase 4; gene trap AJ0315, Wellcome Trust Sanger Institute
MGI ID: MGI:3820519
Synonyms: Mst1-
Gene: Stk4  Location: Chr2:164074113-164155524 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Mutation
origin
Mutant Cell Line:  AJ0315
Germline Transmission:  Earliest citation of germline transmission: J:140710
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsThe gene trap vector inserted between exons 1 and 2. The transcript consists of the first 70 bp of Stk4 fused to the reporter construct. Western blot analysis confirms the expression of a truncated protein. (J:140710)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:  18 strains or lines available
References
Original:  J:140710 Anguera MC, et al., Characterization of two Mst1-deficient mouse models. Dev Dyn. 2008 Nov;237(11):3424-34
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/07/2020
MGI 6.15
The Jackson Laboratory