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Arhgef9tm1Betz
Targeted Allele Detail
Nomenclature
Symbol: Arhgef9tm1Betz
Name: CDC42 guanine nucleotide exchange factor (GEF) 9; targeted mutation 1, Heinrich Betz
MGI ID: MGI:3820313
Synonyms: Cb(+)
Gene: Arhgef9  Location: ChrX:94092541-94240462 bp, - strand  Genetic Position: ChrX, 41.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141850
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 5 and a single loxP site was inserted downstream of exon 5. The neo cassette was then removed by Cre mediated recombination leaving exon 5 floxed. (J:124926, J:141850)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arhgef9 Mutation:  6 strains or lines available
References
Original:  J:141850 Papadopoulos T, et al., Collybistin is required for both the formation and maintenance of GABAergic postsynapses in the hippocampus. Mol Cell Neurosci. 2008 Oct;39(2):161-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory