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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arhgef9tm1Betz
targeted mutation 1, Heinrich Betz
MGI:3820313
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Arhgef9tm1Betz/Y
Tg(Camk2a-cre)2834Lusc/0 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3820315
cn2
 		Arhgef9tm1Betz/Y
Emx1tm1(cre)Yql/Emx1+ 		involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 MGI:3820316


Genotype
MGI:3820315
cn1
Allelic
Composition		 Arhgef9tm1Betz/Y
Tg(Camk2a-cre)2834Lusc/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgef9tm1Betz mutation (0 available); any Arhgef9 mutation (6 available)
Tg(Camk2a-cre)2834Lusc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron morphology ( J:141850 )
• reduction in gephyrin cluster density in the hippocampus at P60 and P130 but not at P40
• however, clustering is unaffected in other areas of the brain




Genotype
MGI:3820316
cn2
Allelic
Composition		 Arhgef9tm1Betz/Y
Emx1tm1(cre)Yql/Emx1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgef9tm1Betz mutation (0 available); any Arhgef9 mutation (6 available)
Emx1tm1(cre)Yql mutation (0 available); any Emx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron morphology ( J:141850 )
• strong reduction in gephyrin cluster numbers in the hippocampus at P40, P60 and P130
• however, clustering is unaffected in other areas of the brain




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory