DymGt(GTR1.3)1Rul
Gene trapped Allele Detail
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Symbol: |
DymGt(GTR1.3)1Rul |
Name: |
dymeclin; gene trap 1, H Earl Ruley |
MGI ID: |
MGI:3817312 |
Gene: |
Dym Location: Chr18:75151852-75420035 bp, + strand Genetic Position: Chr18, 50.97 cM, cytoband E2
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Alliance: |
DymGt(GTR1.3)1Rul page
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DymGt(GTR1.3)1Rul/DymGt(GTR1.3)1Rul mice display growth plate abnormalities
Show the 5 phenotype image(s) involving this allele.
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Mutant Cell Line: |
b3p1h1 |
Germline Transmission: |
Earliest citation of germline transmission:
J:141099
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Parent Cell Line: |
AC1 (ES Cell)
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Strain of Origin: |
129/Sv
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGTR1.3
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Mutation details: The retrovirus gene trap vector GTR1.3 containing a puro gene, a lacZ gene, a Pol2 gene and a neo cassette was inserted into intron 16. The fusion transcript lacks exon 17 and encodes a fusion protein that replaces the last 49 amino acids with 137 irrelevant residues.
(J:137511, J:141099)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
132 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dym Mutation: |
59 strains or lines available
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Original: |
J:141099 Osipovich AB, et al., Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16171-6 |
All: |
3 reference(s) |
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