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| Caption | Sections of proximal tibial and distal femoral epiphysis were examined in wild-type (A,C,E,G,I,L,O) and DymGt(GTR1.3)1Rul/DymGt(GTR1.3)1Rul (B,D,F,H,J,M,P,Q) mice at 2 weeks (A and B), 1 month (C-N), and 6 months of age (O-Q). Sections were stained with either Gomori's trichrome blue (A-D, O-Q) or safranin O (E-H), or were analyzed for BrdU incorporation (I and J) or for caspase 3 expression (L and M). Several islands of chondrocytes within ossified regions (*), and BrdU- and caspase-positive cells (arrows) are indicated. The graphs display the percentage of cells in the proliferative or hypertrophic zones that stained for BrdU incorporation (K) or caspase 3 expression (N), respectively. | ||||
| Copyright | This image is from Osipovich AB, Proc Natl Acad Sci U S A 2008 Oct 21;105(42):16171-6. Copyright 2008 National Academy of Sciences, U.S.A. J:141099 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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