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Tab1tm1.1Mis
Targeted Allele Detail
Nomenclature
Symbol: Tab1tm1.1Mis
Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1; targeted mutation 1.1, Yuji Mishina
MGI ID: MGI:3814197
Synonyms: Tab1deltaE
Gene: Tab1  Location: Chr15:80133127-80161707 bp, + strand  Genetic Position: Chr15, 37.85 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140317
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove the neo cassette along with exons 9 and 10. The absence of protein expression was confirmed by western blot analysis on E16.5 brain extracts. (J:140317)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tab1 Mutation:  59 strains or lines available
References
Original:  J:140317 Inagaki M, et al., Generation of a conditional mutant allele for Tab1 in mouse. Genesis. 2008 Aug;46(8):431-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory