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Transgene Detail
Symbol: Tg(SV40-Igk4C8)L1Hon
Name: transgene insertion L1, Tasuku Honjo
MGI ID: MGI:3813630
Synonyms: L1
Transgene: Tg(SV40-Igk4C8)L1Hon  Location: unknown  
Strain of Origin:  C57BL/6
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(SV40-Igk4C8)L1Hon expresses 1 gene
Mutation detailsThis transgene consists of a 1.3 kb fragment containing promoter and initiation sequence from SV40 and a 5.6 kb fragment extending from the promoter to the constant region of the Igk from the 4C8 hybridoma. The 4C8 hybridoma contains immunoglobulin genes that encode an anti-murine erythrocyte autoantibody. Two lines were generated, this a representative record for both lines. The HL1line carries about 20 copies of the transgene on an autosome. RNase protection analysis confirmed expression of the transgene in lymphoid tissues. (J:139864)
View phenotypes and curated references for all genotypes (concatenated display).
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:139864 Okamoto M, et al., A transgenic model of autoimmune hemolytic anemia. J Exp Med. 1992 Jan 1;175(1):71-9
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.13
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