About   Help   FAQ
Transgene Detail
Symbol: Tg(SV40-Igk4C8)L1Hon
Name: transgene insertion L1, Tasuku Honjo
MGI ID: MGI:3813630
Synonyms: L1
Transgene: Tg(SV40-Igk4C8)L1Hon  Location: unknown  
Strain of Origin:  C57BL/6
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(SV40-Igk4C8)L1Hon expresses 1 gene
Mutation detailsThis transgene consists of a 1.3 kb fragment containing promoter and initiation sequence from SV40 and a 5.6 kb fragment extending from the promoter to the constant region of the Igk from the 4C8 hybridoma. The 4C8 hybridoma contains immunoglobulin genes that encode an anti-murine erythrocyte autoantibody. Two lines were generated, this a representative record for both lines. The HL1line carries about 20 copies of the transgene on an autosome. RNase protection analysis confirmed expression of the transgene in lymphoid tissues. (J:139864)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:139864 Okamoto M, et al., A transgenic model of autoimmune hemolytic anemia. J Exp Med. 1992 Jan 1;175(1):71-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory