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Tg(Igk*A)A02Dgs
Transgene Detail
Nomenclature
Symbol: Tg(Igk*A)A02Dgs
Name: transgene insertion A02, David Schatz
MGI ID: MGI:3811481
Synonyms: TgA
Transgene: Tg(Igk*A)A02Dgs  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 and SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Igk*A)A02Dgs expresses 1 gene
 
Mutation detailsVk167/PEPS is a transgene with a truncated region upstream of the promoter. The Igk (immunoglobulin kappa) sequence was further modified in the current strain through the insertion of 5 tandem repeats of a 20-bp adenine/thymine (A/T) fragment near the 3' end of the variable region. This "TgA" line has an A/T sequence comparable to that found in line "TgG" without the single cytosine:guanine (C:G) insert. (J:139793)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:139793 Unniraman S, et al., Strand-biased spreading of mutations during somatic hypermutation. Science. 2007 Aug 31;317(5842):1227-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory