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Targeted Allele Detail
Symbol: Kat2atm3.2Roth
Name: K(lysine) acetyltransferase 2A; targeted mutation 3.2, Sharon Y R Dent
MGI ID: MGI:3801276
Synonyms: Gcn5flox
Gene: Kat2a  Location: Chr11:100704746-100712465 bp, - strand  Genetic Position: Chr11, 63.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:132940
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 18. Germ line, cre-mediated recombination was used to remove the neo cassette leaving exons 3 through 18 floxed. (J:132940)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat2a Mutation:  15 strains or lines available
Original:  J:132940 Lin W, et al., Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos. Dev Dyn. 2008 Apr;237(4):928-40
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.04
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