Castor1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Castor1^{tm1(KOMP)Vlcg}
• Name: cytosolic arginine sensor for mTORC1 subunit 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3799997
• Synonyms: 2410008K03Rik^tm1Vlcg
• Gene: Castor1 Location: Chr11:4168225-4172409 bp, + strand Genetic Position: Chr11, 2.94 cM, cytoband A1
• Alliance: Castor1^{tm1(KOMP)Vlcg} page
• IMPC: Castor1 gene page

Mutation origin

• Mutant Cell Lines: 10288A-B1, 10288B-B3, 10288B-D12, 10288B-G4
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3833bp between positions 4168298-4172130 of Chromosome 11 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Castor1 Mutation: 23 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)