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Radiation induced Allele Detail
Symbol: Del(5D5Mit73-D5Mit351)5Jcs
Name: deletion, Chr 5, John C. Schimenti 5; deletion, Chr 5, John C Schimenti 5
MGI ID: MGI:3798174
Synonyms: Del5Jcs, Hdhdf4J
Gene: Del(5D5Mit73-D5Mit351)5Jcs  Location: Chr5:26600987-37019120 bp  Genetic Position: Chr5, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:63451
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Allele Type:    Radiation induced
Mutation:    Intergenic deletion
  Del(5D5Mit73-D5Mit351)5Jcs involves 240 genes/genome features (E230008O15Rik, Gm2545, Gm2183 ...) View all
Mutation detailsTargeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Htt locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into C57BL/6J blastocysts. The deletion includes the full Wolf-Hirschhorn syndrome critical region. (J:63451)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(5D5Mit73-D5Mit351)5Jcs Mutation:  0 strains or lines available
Original:  J:63451 Schimenti JC, et al., Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Genome Res. 2000 Jul;10(7):1043-50
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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