Pcdha^tm2Tyag
Targeted Allele Detail

Summary

• Symbol: Pcdha^tm2Tyag
• Name: protocadherin alpha cluster; targeted mutation 2, Takeshi Yagi
• MGI ID: MGI:3797609
• Synonyms: Pcdha^deltaB
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136920
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified isoform(s))
• Mutation: Insertion
• Mutation details: A termination codon followed by a loxP site was inserted at the first codon of alternative exon CR3b which is specific to the B type isoforms. A floxed neo was also inserted for selection purposes and subsequently removed by germ line, cre-mediated recombination. (J:136920)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:136920 Hasegawa S, et al., The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Mol Cell Neurosci. 2008 May;38(1):66-79
• All: 1 reference(s)