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Slc17a8tm1Selm
Targeted Allele Detail
Nomenclature
Symbol: Slc17a8tm1Selm
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; targeted mutation 1, Salah El Mestikawy
MGI ID: MGI:3794893
Synonyms: Vglut3-
Gene: Slc17a8  Location: Chr10:89574020-89621249 bp, - strand  Genetic Position: Chr10, 44.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135586
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with an frt-flanked neo cassette, which is read through during transcription. This results in creation of a stop codon in exon3. The absence of protein product was confirmed by immunohistochemistry on brain sections. (J:135586, J:139493)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc17a8 Mutation:  29 strains or lines available
References
Original:  J:135586 Gras C, et al., The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone. Nat Neurosci. 2008 Mar;11(3):292-300
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory