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Targeted Allele Detail
Symbol: Akt1tm1Pnt
Name: thymoma viral proto-oncogene 1; targeted mutation 1, Philip N Tsichlis
MGI ID: MGI:3794787
Synonyms: Akt1fl
Gene: Akt1  Location: Chr12:112653821-112674796 bp, - strand  Genetic Position: Chr12, 61.2 cM, cytoband F1-F2
Germline Transmission:  Earliest citation of germline transmission: J:135903
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 4. (J:135903)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akt1 Mutation:  24 strains or lines available
Original:  J:135903 Mao C, et al., Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol. 2007 May 1;178(9):5443-53
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory