Hs6st1^tm1Wvc
Targeted Allele Detail

Summary

• Symbol: Hs6st1^tm1Wvc
• Name: heparan sulfate 6-O-sulfotransferase 1; targeted mutation 1, Wellington V Cardoso
• MGI ID: MGI:3793786
• Gene: Hs6st1 Location: Chr1:36107481-36145527 bp, + strand Genetic Position: Chr1, 15.15 cM, cytoband B
• Alliance: Hs6st1^tm1Wvc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135241
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 3' loxP was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. (J:135241)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Hs6st1 Mutation: 26 strains or lines available

References

• Original: J:135241 Izvolsky KI, et al., Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan;46(1):8-18
• All: 6 reference(s)