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Foxd3tm3Lby
Targeted Allele Detail
Summary
Symbol: Foxd3tm3Lby
Name: forkhead box D3; targeted mutation 3, Patricia A Labosky
MGI ID: MGI:3790794
Synonyms: Foxd3fl, Foxd3flox
Gene: Foxd3  Location: Chr4:99544536-99546859 bp, + strand  Genetic Position: Chr4, 45.71 cM
Alliance: Foxd3tm3Lby page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134482
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt-flanked neo cassette with a 5' loxP site was inserted downstream of the coding region and an additional loxP site was inserted upstream of the coding region. (J:134482)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 21 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxd3 Mutation:  10 strains or lines available
References
Original:  J:134482 Teng L, et al., Requirement for Foxd3 in the maintenance of neural crest progenitors. Development. 2008 May;135(9):1615-24
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory