About   Help   FAQ
Stim1tm1.1Rao
Targeted Allele Detail
Summary
Symbol: Stim1tm1.1Rao
Name: stromal interaction molecule 1; targeted mutation 1.1, Anjana Rao
MGI ID: MGI:3778912
Gene: Stim1  Location: Chr7:101917013-102086526 bp, + strand  Genetic Position: Chr7, 54.71 cM
Alliance: Stim1tm1.1Rao page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:133262
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 2 was removed by germ-line, cre-meditated recombination. Deletion of exon 2 is predicted to result in a frameshift and creation of a premature termination site in the next exon. Authors state that this is a null allele. (J:133262)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stim1 Mutation:  46 strains or lines available
References
Original:  J:133262 Oh-Hora M, et al., Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol. 2008 Apr;9(4):432-43
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory