Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation
(0 available);
any
Stim1 mutation
(46 available)
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mortality/aging
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• Background Sensitivity: while Mendelian ratios of embryos are present at E18.5, 38% of mice are born dead on a background with ICR compared to 75% without ICR
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• 50% of mice that are born alive die by 2 days after birth but die within 2 weeks
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growth/size/body
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation
(0 available);
any
Stim1 mutation
(46 available)
|
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mortality/aging
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• Background Sensitivity: while Mendelian ratios of embryos are present at E18.5, 75% of mice are born dead compared to 38% on a background involving ICR
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• all mice that are born alive die by 2 days after birth
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cellular
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• mouse embryonic fibroblasts treated with thapsigargin fail to exhibit a calcium influx unlike in wild-type cells
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation
(0 available);
any
Stim1 mutation
(46 available)
Stim2tm1.1Rao mutation
(0 available);
any
Stim2 mutation
(42 available)
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cellular
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• in mouse embryonic fibroblasts
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