About   Help   FAQ
Nfkbidtm1Clay
Targeted Allele Detail
Nomenclature
Symbol: Nfkbidtm1Clay
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta; targeted mutation 1, Linda K Clayton
MGI ID: MGI:3777661
Synonyms: IkappaBNS-
Gene: Nfkbid  Location: Chr7:30421732-30428746 bp, + strand  Genetic Position: Chr7, 17.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132071
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 4.8 kb region of the gene containing exons 1 through 5 and most of exon 6 was replaced by a neomycin resistance cassette. No gene expression is detected in microarray analysis of homozygote T cells. (J:132071)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Nfkbid Mutation:  12 strains or lines available
References
Original:  J:132071 Touma M, et al., Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. J Immunol. 2007 Aug 1;179(3):1681-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/20/2017
MGI 6.10
The Jackson Laboratory