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Tg(Myh6-Mef2d)2Eno
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Mef2d)2Eno
Name: transgene insertion 2, Eric N Olson
MGI ID: MGI:3776912
Transgene: Tg(Myh6-Mef2d)2Eno  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Mef2d)2Eno expresses 1 gene
 
Mutation detailsMouse cDNA encoding FLAG-tagged mouse Mef2d was put under control of the mouse cardiac myosin heavy chain promoter. The construct also contains the human growth hormone polyA signal. Three transgenic lines were established (1, 2, and 3). Line 2 was more extensively characterized. Western blot analysis shows 15-fold higher levels of Mef2d expression compared to non-transgenic mice. (J:130825)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:130825 Kim Y, et al., The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest. 2008 Jan;118(1):124-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory