About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Mef2d)2Eno
transgene insertion 2, Eric N Olson
MGI:3776912
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Mef2d)2Eno/0 Not Specified MGI:3777091


Genotype
MGI:3777091
tg1
Allelic
Composition		 Tg(Myh6-Mef2d)2Eno/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
liver vascular congestion ( J:130825 )
• liver is severely congested at 8 weeks of age
pulmonary vascular congestion ( J:130825 )
• lungs are severely congested at 8 weeks of age
increased heart atrium size ( J:130825 )
• mice display atrial enlargement at 8 weeks of age
cardiac fibrosis ( J:130825 )
• transgenic animals show extensive fibrosis at 8 weeks of age
cardiomyopathy ( J:130825 )
• hearts display hallmarks of remodeling and cardiomyopathy

muscle
cardiomyopathy ( J:130825 )
• hearts display hallmarks of remodeling and cardiomyopathy

homeostasis/metabolism
abnormal thrombosis ( J:130825 )
• animals show thrombosis at 8 weeks of age

liver/biliary system
liver vascular congestion ( J:130825 )
• liver is severely congested at 8 weeks of age

respiratory system
pulmonary vascular congestion ( J:130825 )
• lungs are severely congested at 8 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory