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RictorGt(RRR347)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: RictorGt(RRR347)Byg
Name: RPTOR independent companion of MTOR, complex 2; gene trap RRR347, BayGenomics
MGI ID: MGI:3775093
Synonyms: Rictor-
Gene: Rictor  Location: Chr15:6708379-6800401 bp, + strand  Genetic Position: Chr15, 3.25 cM, cytoband A1
Mutation
origin
Mutant Cell Line:  RRR347
Germline Transmission:  Earliest citation of germline transmission: J:113443
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap line was found to contain an insertional mutation in the third intron. The mutation results in the production of an in-frame fusion transcript consisting of exons 1-3 from Rictor (amino acids 1-65) and beta-geo. (J:113443)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rictor Mutation:  88 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:113443 Yang Q, et al., Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 2006 Oct 15;20(20):2820-32
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory