About   Help   FAQ
RictorGt(RRR347)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: RictorGt(RRR347)Byg
Name: RPTOR independent companion of MTOR, complex 2; gene trap RRR347, BayGenomics
MGI ID: MGI:3775093
Synonyms: Rictor-
Gene: Rictor  Location: Chr15:6708381-6800398 bp, + strand  Genetic Position: Chr15, 3.25 cM, cytoband A1
Mutation
origin
Mutant Cell Line:  RRR347
Germline Transmission:  Earliest citation of germline transmission: J:113443
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap line was found to contain an insertional mutation in the third intron. The mutation results in the production of an in-frame fusion transcript consisting of exons 1-3 from Rictor (amino acids 1-65) and beta-geo. (J:113443)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rictor Mutation:  82 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:113443 Yang Q, et al., Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 2006 Oct 15;20(20):2820-32
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory