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Rtel1tm1.1Hdin
Targeted Allele Detail
Nomenclature
Symbol: Rtel1tm1.1Hdin
Name: regulator of telomere elongation helicase 1; targeted mutation 1.1, Hao Ding
MGI ID: MGI:3772371
Synonyms: Rteldeltaexon7
Gene: Rtel1  Location: Chr2:181319739-181356616 bp, + strand  Genetic Position: Chr2, 103.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130490
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 7 was removed by germ-line, cre-mediated recombination. Deletion of exon 7 results in a frame shift and premature termination of the peptide. The presence of only the truncated form of the transcript was confirmed by RT-PCR analysis. (J:130490)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rtel1 Mutation:  42 strains or lines available
References
Original:  J:130490 Wu X, et al., Establishment of conditional knockout alleles for the gene encoding the regulator of telomere length (RTEL). Genesis. 2007 Dec;45(12):788-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory