Phenotypes associated with this allele

• Allele Symbol: Rtel1^tm1.1Hdin
• Allele Name: targeted mutation 1.1, Hao Ding
• Allele ID: MGI:3772371
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rtel1^tm1.1Hdin/Rtel1^tm1.1Hdin	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL	MGI:3772441

Genotype
MGI:3772441

hm1

• Allelic Composition: Rtel1^tm1.1Hdin/Rtel1^tm1.1Hdin
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:130490 )

• mice do not survive past E11.5

embryo

abnormal neural tube morphology ( J:130490 )

• at E9.5 to 10.5, mice exhibit neural defects that recapitulate phenotypes observed in Rtel1^tm1Pml

enlarged allantois ( J:130490 )

• at E9.5 to 10.5, mice exhibit a bulbous allantois

abnormal placenta morphology ( J:130490 )

• at E10.5, mice exhibit placental effusion

cardiovascular system

pericardial effusion ( J:130490 )

nervous system

abnormal neural tube morphology ( J:130490 )

• at E9.5 to 10.5, mice exhibit neural defects that recapitulate phenotypes observed in Rtel1^tm1Pml

homeostasis/metabolism

pericardial effusion ( J:130490 )