Tg(Nes-cre/ERT2)KEisc
Transgene Detail
|
Symbol: |
Tg(Nes-cre/ERT2)KEisc |
Name: |
transgene insertion K, Amelia Eisch |
MGI ID: |
MGI:3767432 |
Synonyms: |
Nestin-CreERT2, Tg(Nes-cre/ERT2)KJejo, Tg(Nes-cre/ESR1)KJejo, Tg(Nes-cre)KJejo |
Transgene: |
Tg(Nes-cre/ERT2)KEisc Location: unknown
|
Alliance: |
Tg(Nes-cre/ERT2)KEisc page
|
|
|
Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
Inducer: |
|
tamoxifen |
Mutation: |
|
Insertion
|
|
|
Tg(Nes-cre/ERT2)KEisc expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Homolog in Mouse |
Note |
rat |
Nes (25491) |
|
|
|
|
|
Mutation details: The Nestin-cre/ERT2 transgene was designed with the rat nestin (Nes) promoter driving expression of a CreERT2 fusion gene (cre/ERT2; Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand-binding domain). The transgene was microinjected into fertilized C57BL/6J oocytes, and line K was established.
(J:117032, J:141562)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Nes
(rat)
|
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
Original: |
J:117032 Battiste J, et al., Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development. 2007 Jan;134(2):285-93 |
All: |
122 reference(s) |
|