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Gbatm2Karl
Targeted Allele Detail
Nomenclature
Symbol: Gbatm2Karl
Name: glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
MGI ID: MGI:3764510
Synonyms: gbalnl
Gene: Gba  Location: Chr3:89202928-89208681 bp, + strand  Genetic Position: Chr3, 39.01 cM
Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display a severe and rapidly progressive neurological disease

Show the 6 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127108
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gba Mutation:  10 strains or lines available
References
Original:  J:127108 Enquist IB, et al., Murine models of acute neuronopathic Gaucher disease. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17483-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory