Pcolce2^tm1Ccb
Targeted Allele Detail

Summary

• Symbol: Pcolce2^tm1Ccb
• Name: procollagen C-endopeptidase enhancer 2; targeted mutation 1, Conrad C Bleul
• MGI ID: MGI:3722112
• Synonyms: PCPE2 KO
• Gene: Pcolce2 Location: Chr9:95519681-95577604 bp, + strand Genetic Position: Chr9, 50.18 cM
• Alliance: Pcolce2^tm1Ccb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124347
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace the coding sequence of exon 3, corresponding to nucleotides 258-431, with an IRES-lacZ/neo cassette. (J:124347)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcolce2 Mutation: 32 strains or lines available

References

• Original: J:124347 Heinzel K, et al., The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis. Eur J Immunol. 2007 Sep;37(9):2562-71
• All: 5 reference(s)