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Map2k1tm1Chrn
Targeted Allele Detail
Summary
Symbol: Map2k1tm1Chrn
Name: mitogen-activated protein kinase kinase 1; targeted mutation 1, Jean Charron
MGI ID: MGI:3714918
Synonyms: Map2k1floxed, Mek1fl
Gene: Map2k1  Location: Chr9:64093066-64160887 bp, - strand  Genetic Position: Chr9, 34.55 cM
Alliance: Map2k1tm1Chrn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112223
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 3 is floxed and can be removed by Cre recombination to create a null allele. (J:112223)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 RNA-Seq or microarray experiment(s)
Tumor Data
List all tumor models in MMHCdb carrying Map2k1tm1Chrn
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Map2k1 Mutation:  92 strains or lines available
References
Original:  J:112223 Bissonauth V, et al., Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis. Development. 2006 Sep;133(17):3429-40
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory