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Tg(IgkAb36-71)1Wys
Transgene Detail
Summary
Symbol: Tg(IgkAb36-71)1Wys
Name: transgene insertion 1, Lawrence J Wysocki
MGI ID: MGI:3713815
Synonyms: kappaTg, Tg(IgkAb36-65)1Wys
Transgene: Tg(IgkAb36-71)1Wys  Location: unknown  
Alliance: Tg(IgkAb36-71)1Wys page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IgkAb36-71)1Wys expresses 1 gene
 
Mutation detailsA 14kb construct containing a functionally rearranged kappa light chain from hybridoma clone 36-71 expressing an antibody to p-azophenylarsonate (Ars) and containing natural intron and 3' enhancers was used. The Vk-Jk exon carries 11 amino acid replacements resulting from natural somatic mutagenesis. (J:122260)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:122260 Benschop RJ, et al., Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity. 2001 Jan;14(1):33-43
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory