About   Help   FAQ
Tg(Myh6-rtTA)8585Jam
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-rtTA)8585Jam
Name: transgene insertion 8585, John A McDonald
MGI ID: MGI:3712947
Synonyms: JAM8585, Tg(Myh6-rtTA)1Jam
Transgene: Tg(Myh6-rtTA)8585Jam  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/NTac
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA codon optimized version (for mammalian translation) of the reverse tetracycline transactivator was cloned behind the 5.5kb alpha myosin heavy chain promoter. Reporter construct assays showed that this transgene is uniformly transcribed in cardiac myocytes, and not in various other tissues tested. (J:70619)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:70619 Valencik ML, et al., Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart. Transgenic Res. 2001 Jun;10(3):269-75
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/17/2015
MGI 5.21
The Jackson Laboratory