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Cks1btm1Sir
Targeted Allele Detail
Nomenclature
Symbol: Cks1btm1Sir
Name: CDC28 protein kinase 1b; targeted mutation 1, Steven I Reed
MGI ID: MGI:3711167
Synonyms: Cks1-
Gene: Cks1b  Location: Chr3:89415472-89418383 bp, - strand  Genetic Position: Chr3, 39.11 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121692
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2, which encodes 55% of the protein, was replaced with a neomycin resistance cassette. (J:121692)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cks1b Mutation:  7 strains or lines available
References
Original:  J:121692 Spruck C, et al., A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1. Mol Cell. 2001 Mar;7(3):639-50
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory