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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm3(SS18/EGFP)Mrc
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Mario R Capecchi
MGI ID: MGI:3710098
Synonyms: Rosa26hSS2, SSM2
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:120967
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter)
Mutation:    Insertion
Gt(ROSA)26Sortm3(SS18/EGFP)Mrc expresses 1 gene
Mutation detailsThese mice express human synovial sarcoma translocation, chromosome 18-IRES-EGFP bicistronic mRNA from the ROSA promoter. The vector also contained a strong transcriptional termination signal, NeoPA, flanked by loxP sites, such that the inserted cDNA is not transcribed without the presence of cre recombinase. (J:120967)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  434 strains or lines available
Original:  J:120967 Haldar M, et al., A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell. 2007 Apr;11(4):375-88
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory