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Foxe3tm1Pca
Targeted Allele Detail
Summary
Symbol: Foxe3tm1Pca
Name: forkhead box E3; targeted mutation 1, Peter Carlsson
MGI ID: MGI:3707205
Synonyms: Foxe3tm
Gene: Foxe3  Location: Chr4:114782344-114783210 bp, - strand  Genetic Position: Chr4, 52.73 cM, cytoband C7
Alliance: Foxe3tm1Pca page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119940
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The forkhead box was replaced by a lacZ-PGK-neo cassette. (J:119940)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 10 assay results
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxe3 Mutation:  15 strains or lines available
References
Original:  J:119940 Blixt A, et al., Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol. 2007 Feb 1;302(1):218-29
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory