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Mmp13tm1Jdar
Targeted Allele Detail
Nomenclature
Symbol: Mmp13tm1Jdar
Name: matrix metallopeptidase 13; targeted mutation 1, Jeanine D'Armiento
MGI ID: MGI:3706953
Synonyms: Mmp13-
Gene: Mmp13  Location: Chr9:7272514-7283333 bp, + strand  Genetic Position: Chr9, 2.46 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120352
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Not Specified
 
Mutation detailsAn EGFP (d2EGFP) and neomycin resistance cassette replaced exons 1 through 10. Western blot analysis confirmed the absence of protein expression in mouse embryonic cells. (J:197595)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mmp13 Mutation:  14 strains or lines available
References
Original:  J:120352 Kosaki N, et al., Impaired bone fracture healing in matrix metalloproteinase-13 deficient mice. Biochem Biophys Res Commun. 2007 Mar 23;354(4):846-51
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory