About   Help   FAQ
Ptf1atm1(cre)Hnak
Targeted Allele Detail
Nomenclature
Symbol: Ptf1atm1(cre)Hnak
Name: pancreas specific transcription factor, 1a; targeted mutation 1, Hassan Nakhai
MGI ID: MGI:3701996
Synonyms: p48-cre, Ptf1a-cre(ex1), Ptf1aCre(ex1), Ptf1atm1(cre)Nak
Gene: Ptf1a  Location: Chr2:19445663-19447501 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119184
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsCre recombinase replaced part of exon 1. A neomycin resistance gene included in the vector was subsequently removed via transient FLP expression. (J:119184)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ptf1a     Summary of all recombinase alleles driven by Ptf1a. Comparative matrix view of recombinase activities
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  18 strains or lines available
References
Original:  J:119184 Nakhai H, et al., Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Development. 2007 Mar;134(6):1151-60
All:  29 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory