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Spry4tm1.2Mrt
Targeted Allele Detail
Nomenclature
Symbol: Spry4tm1.2Mrt
Name: sprouty homolog 4 (Drosophila); targeted mutation 1.2, Gail R Martin
MGI ID: MGI:3701941
Synonyms: Spry4deltaORF
Gene: Spry4  Location: Chr18:38586268-38601268 bp, - strand  Genetic Position: Chr18, 20.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119280
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe entire open reading frame was deleted by flp-mediated removal of a neo cassette in the opposite orientation and a cre-mediated recombination of a floxed open reading frame. (J:119280)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Spry4 Mutation:  36 strains or lines available
References
Original:  J:119280 Klein OD, et al., Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell. 2006 Aug;11(2):181-90
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory