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Mapkapk5tm1Pqs
Targeted Allele Detail
Nomenclature
Symbol: Mapkapk5tm1Pqs
Name: MAP kinase-activated protein kinase 5; targeted mutation 1, Peiqing Sun
MGI ID: MGI:3698841
Synonyms: deltaex8, Prak-
Gene: Mapkapk5  Location: Chr5:121525038-121545905 bp, - strand  Genetic Position: Chr5, 61.84 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117893
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into exon 8. Protein was not detected in mutant mice. (J:117893)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapkapk5 Mutation:  21 strains or lines available
References
Original:  J:117893 Sun P, et al., PRAK is essential for ras-induced senescence and tumor suppression. Cell. 2007 Jan 26;128(2):295-308
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory