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G6pc3tm1Rmob
Targeted Allele Detail
Nomenclature
Symbol: G6pc3tm1Rmob
Name: glucose 6 phosphatase, catalytic, 3; targeted mutation 1, Richard M O'Brien
MGI ID: MGI:3697438
Synonyms: UGRP-
Gene: G6pc3  Location: Chr11:102189699-102194081 bp, + strand  Genetic Position: Chr11, 65.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117664
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector was designed to replace exon 1 and 10 bp of intron 1 with a lacZ-neo cassette. (J:117664)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any G6pc3 Mutation:  3 strains or lines available
References
Original:  J:117664 Wang Y, et al., Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon. J Biol Chem. 2006 Dec 29;281(52):39982-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/07/2019
MGI 6.14
The Jackson Laboratory