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Il10tm2Roer
Targeted Allele Detail
Nomenclature
Symbol: Il10tm2Roer
Name: interleukin 10; targeted mutation 2, Axel Roers
MGI ID: MGI:3696059
Synonyms: IL-10FL
Gene: Il10  Location: Chr1:131019845-131024970 bp, + strand  Genetic Position: Chr1, 56.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117122
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    The insertion of loxP sites flanking exon 1 created this allele. (J:117122)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il10 Mutation:  32 strains or lines available
References
Original:  J:117122 Siewe L, et al., Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA. Eur J Immunol. 2006 Dec;36(12):3248-55
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory