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Arhgap32tm1Taki
Targeted Allele Detail
Nomenclature
Symbol: Arhgap32tm1Taki
Name: Rho GTPase activating protein 32; targeted mutation 1, Tetsu Akiyama
MGI ID: MGI:3694810
Synonyms: PX-RICS-, RICS-
Gene: Arhgap32  Location: Chr9:32116136-32268446 bp, + strand  Genetic Position: Chr9, 17.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116446
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A lacZ-neo cassette was inserted at the ATG. Western blot failed to detect protein in mutant mice. (J:116446)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arhgap32 Mutation:  51 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Autism Spectrum Disorder in Jacobsen Syndrome J: 236753.
References
Original:  J:116446 Nasu-Nishimura Y, et al., Role of the Rho GTPase-activating protein RICS in neurite outgrowth. Genes Cells. 2006 Jun;11(6):607-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory