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Gene trapped Allele Detail
Symbol: Akap8Gt(XG068)Byg
Name: A kinase (PRKA) anchor protein 8; gene trap XG068, BayGenomics
MGI ID: MGI:3694775
Synonyms: Akap95GT
Gene: Akap8  Location: Chr17:32303672-32321238 bp, - strand  Genetic Position: Chr17, 17.48 cM, cytoband B2
Cleft palate in Akap8Gt(XG068)Byg/Akap8Gt(XG068)Byg Fignfi/Fignfi mice

Show the 1 phenotype image(s) involving this allele.

Mutant Cell Line:  XG068
Germline Transmission:  Earliest citation of germline transmission: J:116474
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped (Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
Mutation detailsA gene trap vector containing En2-betageo-pA was inserted into intron 8, resulting in the loss of the C-terminal 334 amino acids. (J:116474)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akap8 Mutation:  18 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:116474 Yang Y, et al., Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse. J Biol Chem. 2006 Aug 4;281(31):22352-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory