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Targeted Allele Detail
Symbol: Il2rgtm1Krf
Name: interleukin 2 receptor, gamma chain; targeted mutation 1, Paul Krimpenfort
MGI ID: MGI:3690461
Synonyms: gammac, IL-2Rgammac-
Gene: Il2rg  Location: ChrX:101264378-101268255 bp, - strand  Genetic Position: ChrX, 43.9 cM
Germline Transmission:  Earliest citation of germline transmission: J:123682
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    All coding exons are replaced by a pgk-hygromycin cassette. (J:114561)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il2rg Mutation:  72 strains or lines available
Original:  J:123682 Blom B, et al., The role of the common gamma chain of the IL-2, IL-4, IL-7 and IL-15 receptors in development of lymphocytes, constitutive of Bcl-2 does not rescue the developmental defects in gamma common-defiecent mice, in Cytokines and Growth Factors in Blood Transfusion. 1997:3-12.
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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