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Ucp2Gt(S20-3G1)Sor
Gene trapped Allele Detail
Nomenclature
Symbol: Ucp2Gt(S20-3G1)Sor
Name: uncoupling protein 2 (mitochondrial, proton carrier); gene trap S20-3G1, Philippe Soriano
MGI ID: MGI:3687318
Synonyms: Ucp2Gt(FHCRC-GT-S20-3G1)Sor
Gene: Ucp2  Location: Chr7:100142544-100148836 bp, + strand  Genetic Position: Chr7, 54.36 cM
Mutation
origin
Mutant Cell Line:  S20-3G1
Germline Transmission:  Earliest citation of germline transmission: J:113539
Parent Cell Line:  AK7.1 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: ROSAFARY
 
Mutation detailsA gene trap vector containing both Betagal and a neomycin cassette inserted into the locus. Northern blot confirmed absence of transcript in mutant mice. Western blot failed to detect protein in mutant spleen samples. (J:113539)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ucp2 Mutation:  36 strains or lines available
References
Original:  J:113539 Horvath B, et al., Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. Biochem Pharmacol. 2002 Aug 1;64(3):369-74
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory