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Rhohtm1Daw
Targeted Allele Detail
Nomenclature
Symbol: Rhohtm1Daw
Name: ras homolog family member H; targeted mutation 1, David A Williams
MGI ID: MGI:3687310
Synonyms: Rhoh-
Gene: Rhoh  Location: Chr5:65861213-65896700 bp, + strand  Genetic Position: Chr5, 33.8 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113565
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced the entire coding region, located in exon 3. Absence of protein was confirmed by immunoblot analysis. (J:113565)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rhoh Mutation:  6 strains or lines available
References
Original:  J:113565 Gu Y, et al., RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development. Nat Immunol. 2006 Nov;7(11):1182-1190
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory