All Phenotypes Rhoh<tm1Daw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rhoh^tm1Daw
targeted mutation 1, David A Williams
MGI:3687310

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rhoh^tm1Daw/Rhoh^tm1Daw	involves: 129 * C57BL/6	MGI:3690086

Allelic Composition	Rhoh^tm1Daw/Rhoh^tm1Daw
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhoh^tm1Daw mutation (0 available); any Rhoh mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

thymus hypoplasia ( J:113565 )

• mutant thymuses were much smaller than wild-type

• thymic cellularity was 30% that of wild-type

arrested T cell differentiation ( J:113565 )

decreased T cell number ( J:113565 )

• T cell lymphopenia of the peripheral blood, spleen and lymph node

immune system

thymus hypoplasia ( J:113565 )

• mutant thymuses were much smaller than wild-type

• thymic cellularity was 30% that of wild-type

arrested T cell differentiation ( J:113565 )

decreased T cell number ( J:113565 )

• T cell lymphopenia of the peripheral blood, spleen and lymph node

endocrine/exocrine glands

thymus hypoplasia ( J:113565 )

• mutant thymuses were much smaller than wild-type

• thymic cellularity was 30% that of wild-type

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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