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Targeted Allele Detail
Symbol: P2rx4tm1Rass
Name: purinergic receptor P2X, ligand-gated ion channel 4; targeted mutation 1, Francois Rassendren PhD
MGI ID: MGI:3665297
Synonyms: P2rx4tm1Rano, P2X4-
Gene: P2rx4  Location: Chr5:122707544-122729738 bp, + strand  Genetic Position: Chr5, 62.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:112177
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 1, including the ATG, and part of intron 1 was replaced by a lacZ cassette. Western blot confirmed absence of protein in mutant brain, lung and submandibular gland samples. (J:112177)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2rx4 Mutation:  11 strains or lines available
Original:  J:112177 Sim JA, et al., Altered hippocampal synaptic potentiation in P2X4 knock-out mice. J Neurosci. 2006 Aug 30;26(35):9006-9
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
The Jackson Laboratory