About   Help   FAQ
Nlrc4tm1Nnz
Targeted Allele Detail
Nomenclature
Symbol: Nlrc4tm1Nnz
Name: NLR family, CARD domain containing 4; targeted mutation 1, Gabriel Nunez
MGI ID: MGI:3664623
Synonyms: Card12-, Ipaf-, IPAF-, Nlrc4-
Gene: Nlrc4  Location: Chr17:74426255-74459144 bp, - strand  Genetic Position: Chr17, 45.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112671
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1 and 2 were replaced with an IRES-Betageo. (J:112671)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrc4 Mutation:  41 strains or lines available
References
Original:  J:112671 Franchi L, et al., Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol. 2006 Jun;7(6):576-82
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/11/2020
MGI 6.14
The Jackson Laboratory