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Adipoqtm1Far
Targeted Allele Detail
Nomenclature
Symbol: Adipoqtm1Far
Name: adiponectin, C1Q and collagen domain containing; targeted mutation 1, Bob Farese
MGI ID: MGI:3663753
Synonyms: Adipoq-, Adipoqtm1Rvf
Gene: Adipoq  Location: Chr16:23146536-23157968 bp, + strand  Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111346
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 2 with a neomycin resistance cassette. Protein was not detected by ELISA or immunoblotting, confirming the complete ablation of the locus. (J:111346)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adipoq Mutation:  29 strains or lines available
References
Original:  J:111346 Streeper RS, et al., Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin. Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E388-94
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory